Time-of-flight mass spectrometry

Introduction to LCMS-IT-TOF Time of Flight Mass Spectrometry Series

The name LCMS-IT-TOF is derived from the name of Shimadzu's single-stage quadrupole liquid chromatography-mass spectrometer LCMS-2010. LCMS stands for liquid chromatography-mass spectrometry. The front end of LCMS-IT-TOF is similar in structure to LCMS-2010, with the addition of Shimadzu's ion trap time-of-flight mass spectrometry, hence the name LCMS-IT-TOF. LCMS-IT-TOFTime-of-flight mass spectrometryIt can be widely applied in the structural analysis of organic small molecules, identification of traditional Chinese medicine components, identification of food, spices, agricultural and animal residues, identification of drug metabolites, proteomic research of biomolecules, including primary de novo sequencing of peptides, protein identification, post transcriptional modification, analysis of complex glycoproteins, etc. Among them, the prediction of unknown compound molecular formulas is its most distinctive function. By analyzing multi-level high-quality precision fragments of unknown compounds, the elements and chemical formula of the compound can be quickly determined, thereby obtaining the basic information of the compound. Therefore, LCMS-IT-TOF is a high-performance liquid chromatography ion trap time-of-flight mass spectrometer with comprehensive functions, high resolution, high quality accuracy, and multi-level mass spectrometry capabilities.