Thermo Orbitrap Eclipse Trilid Mass Spectrometer

22020beltETDofThermo Orbitrap Eclipse Triridmass spectrometer

beltETDofThermo Orbitrap Eclipse Triridmass spectrometer

HMRn (High Mass Range MSn): The molecular weight range of MSn multi-stage mass spectrometry can reach 8000 Da, including extended Orbitrap m/z to 8000 and LTQ separation of parent ions m/z to 8000, and has MSn (n=1-10) capability. For example, using HMRn for NativeMics can identify ligands of membrane proteins using multi-stage mass spectrometry, which can better understand protein interactions.
(2) PTCR (Proton Transfer Charge Reduction) ion source: Perfluorophenanthrene (PFPP) ions, used for subsequent gas-phase ion reactions in a two-stage linear ion trap, utilizing proton transfer to reduce the multi charge states of parent or daughter ions, improving the quality of multi charge spectra, making top-down omics analysis easier, and better revealing hidden features of proteins.
(3) RTS (Real time search) algorithm software: Provides powerful database functionality. When the identified protein matches the initial database, it is marked as no longer performing MS3, which can effectively shorten time and increase throughput by 1 times. When selecting determined parent ions for SPS MS3 quantification, it can improve the accuracy of quantification and the proteomic coverage of TMT experiments.
(4) Hyperbolic QR5 segmented quadrupole: grows to 25 cm and expands in diameter to improve ion transport efficiency, and can selectively separate 0.4 Da parent ions.
(5) It has a resolution of 500000 and can reach a resolution of 1 million after expansion options.