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E-mail
service@aitesenctm.com
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Phone
18118481917
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Address
3106, Comprehensive Building 7, Fangzheng Zhigu, No. 155 Suhong East Road, Suzhou Industrial Park
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Suzhou Aitson Pharmaceutical Equipment Co., Ltd
Specialized high-pressure homogenizer for cell lysis
NegotiableUpdate on 05/26
- Model
- Nature of the Manufacturer
- Producers
- Product Category
- Place of Origin
Overview
Biological specific high-pressure homogenizer HPH-1500l Protein drugs l Bioengineering l Vaccines (human/animal) l Structural biology l Reagent raw materials/latex reagents l Insulin and other cell types and effects Cell types Crushing pressure (bar) Crushing times (times) Crushing rate Large intestine
Product Details
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Biological specific high-pressure homogenizer HPH-1500 l Protein based drugs l Bioengineering l Vaccine (for human use)/Animal use) l Structural Biology l reagent raw material/Latex reagent l insulin, etc. |
Types and effects of fragmented cells
cell type |
Crushing pressure (bar) |
Number of Breaks (times) |
breakage rate |
Escherichia coli |
800~1000 |
1~2 |
＞99% |
yeast |
1200~1400 |
2~5 |
＞95% |
Mammalian cells |
10~300 |
1~2 |
＞99% |
insect cell |
600~1000 |
2~3 |
＞99% |
Spore cell |
1300~1600 |
3~5 |
＞90% |
algal cells |
1200~1500 |
2~4 |
＞95% |
Typical bacterial fragmentation effect diagram
Escherichia coli |
yeast |
yeast |
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break broken front |
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break broken after |
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Technical Features
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Efficient crushing rate The cell/bacterial fragmentation rate can reach99%The above. Variable frequency flow control system The flow rate of the equipment can be adjusted according to the different sample sizes, which can fully meet the requirements of micro experiments and pilot samples. 0residue After the sample is crushed, it can be emptied without any residue. Suitable for amplification requirements The process conditions explored through this equipment can achieve amplification and are suitable for industrialization. Built in cooling system Directly cooling the homogeneous crushing point without any high temperature residence time, the sample temperature can be controlled at4℃Internally, it can fully ensure the activity of protein release after fragmentation. |
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Technical Specifications
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l Product process viscosity:＜2000cPs l Feed particle size: ＜500μm l Feed temperature: ＜90℃ l Output5~15L/H l Minimum single batch processing capacity:20ml~45ml l Homogenization level: Level 1 (crushing) l Design pressure2000bar l working pressure:1500bar l Pressure display: sanitary diaphragm digital display pressure gauge |
l Main motor:1.5kW，8Level,Class. F，IP55 l Voltage and frequency:380V，50Hz，3phase l Level: Sanitary Grade l Piston:1Only, made of ceramic/合金制 l Internal cooling: fan l Incoming and outgoing material connection:Tri-ClampQuick Connect l Cleaning temperature: ＜90℃ l Sterilization temperature: ＜145℃ l wash/Sterilization time:30min |
Principle diagram of high-pressure homogeneous crushing
Core component description
l Pressure module:Split structure, AustriaN690EThe ultra-high hardness special alloy forging module has undergone solid solution testing, ultrasonic inspection, and enhanced heat treatment.
l Pressure plunger:Adopting the NetherlandsTechno Ceramic 99.999%High purity zirconia processing, surface polished to0.2uIt has high wear resistance and can be used on both ends.
l Piston seal:Adopting GermanyGEHRMade from ultra-high molecular weight composite materials, it has compressive sealing properties and self-lubricating function.
l
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