Intestinal barrier function evaluation system

Barrier function is one of the important functions of the intestine. When inflammation occurs in the intestine, the barrier function of intestinal epithelial cells will be damaged, and their transport characteristics will also change. Understanding the changes in intestinal barrier function is of great significance for the prevention and repair of intestinal barrier injury.

The intestinal barrier function evaluation system is composed of an in vitro absorption and transport device for the intestine（C4300 Ussing Chamber）TheVCCMC6PLUSComposition of electrophysiological signal continuous monitoring instrument and data acquisition system.

C4300 Ussing ChamberAs an in vitro absorption and transport device for the intestine, it can maintain physiological activity of isolated intestinal tissue for a longer period of time; The flow paths located on both sides of the intestinal tissue are equivalent to the mucosal and serosal sides of the intestine, used to simulate intestinal absorption and transport; The added transport markers can be sampled according to the set time.

VCCMC6PLUSThe electrophysiological signal continuous monitoring device can not only measure transmembrane resistanceTEERIt can also measure transmembrane voltage simultaneouslyPDShort circuit currentIscAnd conductivityG.

The data collection system continuously collects measurement data in real-time and can collect data simultaneously8All electrophysiological parameters of each channel.

The intestinal barrier function evaluation system has multiple channels to choose from, such as2通道、4通道、6Channel and8The more channels there are, the more specimens can be measured in one experiment.