Thermoelectric spray detector

Which detector works better in HPLC or UHPLC? This question is difficult to answer simply because no detector can meet all detection needs. Although UV detectors are widely used, compounds without UV absorption cannot be detected, and the actual performance of other so-called universal detectors often fails to meet the complex requirements of multiple applications, resulting in detection gaps. This is the limitation of the detector.

Which detector works better in HPLC or UHPLC? This question is difficult to answer simply because no detector can meet all detection needs. Although UV detectors are widely used, compounds without UV absorption cannot be detected, and the actual performance of other so-called universal detectors often fails to meet the complex requirements of multiple applications, resulting in detection gaps. This is the limitation of the detector.

　　Electric spray detector(CAD) was developed by ESA using breakthrough technology. CAD is based on the innovative detection principle of *, which enables analysis tasks that currently need to be completed on different detectors (such as refractive index (RI), low wavelength ultraviolet (UV), evaporative light scattering (ELSD), etc.) to be completed on a universal detector, greatly improving analysis efficiency.

At present, CAD detection technology has been widely accepted by pharmaceutical companies due to its higher sensitivity, wider dynamic monitoring range, and better detection results than other technologies. Its main advantages are as follows: ● High sensitivity ● Good repeatability ● Signal response * ● Wide dynamic monitoring range ● Wide application range ● Intuitive and simple operation

　　Corona electric sprayDetection technology is a powerful supplement to UV and mass spectrometry detectors, which can be practically applied to any non-volatile or semi volatile compound, including: ● drug compounds ● drug scaffold molecules ● carbohydrates ● lipids ● steroids ● peptides ● proteins ● polymers

For any detector, it is very important to accurately determine the analyte over a wide range, but almost every detector has its own focus, which may result in different responses of the same analyte on different detectors, or changes in the mobile phase having different effects on different detectors. The Corona Ultra detection results are related to the analyte particles, and the signal current is proportional to the mass of the analyte in the sample. Therefore, regardless of the compound, as long as the injection mass is the same, the response is basically *Corona Ultra detectorCan detect all non-volatile substances, including substances without chromophores, regardless of the molecular structure of the tested substance.