In the continuous reaction process of flow chemistry, pressure is one of the important parameters affecting the reaction. Especially for reactions involving gases: hydrogenation reaction, oxygen oxidation reaction, supercritical reaction, partial Diels Alder reaction, ammonolysis reaction, etc; The reaction process involves gas generation reactions, such as substitution reactions of diazonium salts, synthesis reactions of nitrogen indole, and low boiling solvent enhanced reaction conditions. Continuous flow equipment is equipped with pressure controllers. The advantage of the fully automatic online back pressure regulation scheme for continuous reaction processes compared to traditional manual pressure regulation is that it can effectively reduce human operation error factors, avoid pressure fluctuations in the reaction system, and achieve constant current and pressure.