Introduction:2018year6moon3~7Day, a grand event in the field of mass spectrometry-American Mass Spectrometry Annual Meeting（66th ASMS, hereinafter referred to asASMS）At the San Diego Convention Center in California, USASan Diego Convention CenterHold it.

At the feast of mass spectrometry workers who witness the collision of new and old technologies, exchange of innovative ideas, and the combination of inheritance and development, Thermo Fisher Scientific has releasedEliminate the dross and preserve the essence, making your analysis more refinedLCMSNew products andsoftware！

Thermo Scientific™Orbitrap ID-XThree in one ultra-high resolution mass spectrometer

Thermo Scientific™Q Exactive UHMRCombined high-resolution mass spectrometer

Thermo Scientific™TSQ FortisTriple quadrupole mass spectrometer

Thermo Scientific^TMCompound Discoverer 3.0

mass spectrometry(Mass Spectrometry，MS)Because of it

• high sensitivity
• High chemical structure resolution
• Ability to analyze complex samples

It has become a tool for compound analysis. However, both small molecule compounds and large molecule compounds exhibitThe characteristics of diversity and complexity constantly pose new challenges to mass spectrometry analysis.

For example, biomolecules usually contain multiple chemical structural isomers, which coexist in a system and play different biological functions. How to sensitively and quantitatively analyze the isomers has always been a great challenge.

How can we improve the performance of mass spectrometry analysis for challenging low abundance, high complexity matrices, or small molecule analytes that are difficult to analyze chemical structures, while also having functions such as automatic data collection and processing, and deeply mining unknown information to increase throughput?(This passage connects the previous and the next)

ASMSAbove, the three products launchedLCMSNew product, removing the dross and preserving the essence, simplifying the process, providing powerful solutions for the analysis of large and small molecule compounds.The analysis of non denaturing proteins and low abundance small molecule compounds indicates a new direction.

Orbitrap ID-XThree in one ultra-high resolution mass spectrometer

Redefine the analysis of unknown small molecule compounds

• Ultra high resolution mass spectrometer for deep expansion of small molecule compound analysis functions
• Automated data collection and processing steps（AcquireX）

Expanded the results obtained by mass spectrometry for challenging low abundance, high complexity matrices, or small molecule analytes with difficult to analyze chemical structures.

Q Exactive UHMRCombined high-resolution mass spectrometer

Non denaturing mass spectrometry and non denaturingTop-downAnalysis function

• achievedOrbitrapUltra high quality scanning range- 80,000 m/z，
• Maintain ultra-high sensitivity and resolution under high-quality detection conditions, while achievingMS²andpseudo-MS³function
• Establish a powerful analytical solution for studying the structure and heterogeneity of protein complexes.

Meanwhile, due to the powerful functions mentioned above,Q Exactive UHMRInTop-downAnalysis provides structural details that cannot be observed by other methods, thusDeepen the understanding of protein function, disease mechanisms, potential drug targets, and biological therapeutic compounds.

TSQ FortisTriple quadrupole mass spectrometer

Quantitative productivity

• Adopting a novel matrix for ion guidance separation（MSIG）Ensure the durability and stability of the instrument while maintaining ion beam transmission
• Thermo Fisher's triple quadrupole family products,Combining the dual advantages of performance and price, it integrates quantitative performance, ultra-high quantitative productivity, ultra fast analysis speed, and ease of use.

Compound Discoverer 3.0

New generation of small molecule compound analysis software

• Rich toolset solves the challenges of small molecule analysis
• Workflow flexibility can meet analytical needs
• Help to learn more about unknown things
• Customizable report

Removing the dross and preserving the essenceQ Exactive UHMRCombined high-resolution mass spectrometer,Orbitrap ID-XThree in one ultra-high resolution mass spectrometer andTSQ FortisTriple quadrupole mass spectrometer provides a powerful solution for the analysis of large and small molecule compounds.

Moving forward, facing the core needs of customers directly

The new product released this time enriches the application areas of Thermo Fisher mass spectrometry solutions, meets the core needs of customers, expands from research depth to academic breadth, uses Thermo Fisher high mass spectrometer to deeply explore the potential of individual samples, analyzes sample composition, and combines its own complete solution to provide new ideas for more disciplines:

Proteomics: Promoting the extension of proteomics applications, from large-scale sample research to more diverse applications;

Characterization of small molecule compounds: identification and characterization of small molecule compounds in translational metabolomics and plasma

Protein characterization: supporting the development of biomedicine and enhancing structural biology research

Qualitative and quantitative analysis: meets the requirementsThe demand for future sample analysis in routine labs