The lives of young and middle-aged people nowadays can be described as a major headache:Don't deny issues such as employment, marriage, childbirth, parenting, and retirement. You have at least been hit by one of them.

Today, let's talk aboutFertility anxiety.

More and more people are choosing to marry later, and the issue of childbirth after marriage has become another "gift proposition" faced by many couples in their marriage.

Living in China, which values traditional family structures, couples who have been married for many years and still live in a two person world often have to bear greater peer and family pressure.

Especially for women, whether they give birth or not, they often bear more pressure and risks.

In fact, reproductive issues, especially reproductive health issues, are more worthy of attention for men's reproductive health.

Why do you say that? Let's take a look at the research of the World Health Organization!

world health organization(WHO)It is estimated that there are currently 60-80 million couples with reproductive dysfunction. The situation varies in different regions, and it is estimated that 8% to 12% of couples are affected by this (2).

Therefore, this is no longer just a personal battle, but also brings huge business opportunities for fertility clinics (2); So in recent years, a number of biological studies have emerged on the causes, diagnosis, and treatment of reproductive disorders.

Recent studies have shown that 45% to 50% of fertility problems are caused by male factors.

Therefore, the research focus of the medical, scientific, and academic communities has also changed accordingly.

But at the same time, the problem is becoming increasingly serious - in recent years, the female infertility rate has effectively decreased, but the male infertility rate is on the rise, mainly affecting young men:The fertility rate of males under * years old has decreased by 15%.3

Therefore, establishing a high-quality male reproductive research laboratory is essential for this research——There are too many variable factors in studying the root causes of male infertility and exploring treatment options.Therefore, it is crucial to equip laboratory equipment that can produce highly reproducible results.

OHAUS ohausWe can provide a variety of safe, compact, and effective equipment for the entire laboratory, and can also select equipment according to experimental needs.

1.

The rate of decline in male fertility is comparable to that of the pandemicSick!

Scientists and researchers have realized the urgency of this issue, and if the male fertility rate continues to decline, the consequences would be unimaginable. Dr. Elizabeth Snyder, an assistant professor in the Department of Animal Sciences at Rutgers University, stated that research has shown that:

In the past decade, the quality of male sperm has been declining, which may lead to a "sub replacement" of the existing population.

“In this case, the population of each generation will be smaller than the previous generation,”Dr. Snyder explained,“The fertility rate is lower than about 2.1 children per woman.”

In addition to its impact on family planning, male infertility can also serve as a biological indicator for other health-related diseases:Men with low sperm quality are at greater risk of other major health problems.

2.
There is still no consensus on what is a killer of male reproductive health

One of the main challenges for scientists and researchers is that the likelihood and direct factors of infertility vary greatly depending on individual cases.

British Medical Research Council(MRC)Richard Sharpe, a professor at the Edinburgh Reproductive Health Centre, believes that there are two factors that make it difficult for them to make accurate predictions and diagnoses:

1、 The quality of human semen is relatively poor.

His research shows that ordinary men produce a large amount of infertile or useless sperm every time. For example, objectively speaking, although the amount of sperm produced by males varies, the effective amount of sperm produced by males each time is the same as that of ordinary hamsters.

2、 The huge differences between individuals also plague research in this field.

Professor Sharpe's 2019 research on the impact of lifestyle and environment on male infertility(Lifestyle and Environmental Contribution to Male Infertility)In the middle, it is written:

“The average quality of human semen is not high, coupled with individual differences and significant variations in the quality of sperm produced by the same male each time, which means that interdisciplinary research on men is a difficult task. We find it difficult to determine whether and how occupation, lifestyle, or other environmental conditions affect semen volume or sperm quality.”

But Sharpe continued to point out some possible occupations and lifestyles, such as exposure to high temperatures or environments containing insecticide odors, or the use of recreational drugs.

However, even so, it is still difficult to determine the cause and consequences. Sharpe pointed out that even though there is evidence that men produce 30% less sperm in summer than in winter, researchers cannot say for sure whether this is simply due to rising temperatures or other factors(such as loose clothing, air conditioning, and other environmental factors)This is an indicator that is constantly changing.

Dr. Snyder believes that:“If we can identify the reasons for the increase in male infertility rates, this study will help improve or control it.”

Regardless of whether it is caused by genes, genetics, environment, diet, or lifestyle habits, scientists such as Dr. Snyder are still determined to study it to the end.

“Our experiment aims to improve male reproductive health by enhancing our understanding of RNA biology in male reproductive cells.These research findings may also have a direct impact on our diagnosis and treatment of infertility, as well as the development of safe and reversible male infertility. “

3.

Male *, future research and development of new blue oceans

Dr. Snyder mentioned that the latter part of the research has become an auxiliary focus of the entire study:非激素型男性*(i.e. the "*" used by men)The development of this technology may make it possible for men to regulate and control their reproductive cycle.

There is currently no oral medication available for men on the market, but this situation may soon change.

National Institutes of Health, United States(NIH)The Male Contraceptive Program Organization(MCI)We are currently funding this non hormone reversible * scientific research project.

Nowadays, a large number of laboratories are focusing on studying the development of sperm in the testes, the impact of sperm function on female reproductive organs, and there are also numerous projects focusing on the factors affecting sperm quality.

It will take some time before the male * goes public, but new investments have already been made, coupled with the dedicated research of scientists and researchers, clinical trials will be just around the corner.

At present, various research institutes are striving to explore various feasible contraceptive methods, including disrupting the development of new sperm, reducing sperm motility, and hindering sperm egg binding.

So far, scientists have obtained a large number of research results, and although these methods are still in the early stages of development, they have shown great potential (4).

But no matter where future scientists' explorations go,

OHAUS ohausWe will always provide them with durable laboratory precision instruments and high-quality sample pretreatment equipment, and firmly support their forward-looking research on human health!

References：

1. Calverton, Maryland, USA: ORC Macro and the World Health Organization; 2004. World Health Organization. Infecundity, Infertility, and Childlessness in Developing Countries. DHS Comparative Reports No 9.

2. Infertility: an international health problem. , Sciarra J, Int J Gynaecol Obstet. 1994 Aug; 46(2):155-63.
3. Infertility and impaired fecundity in the United States, 1982-2010: data from the National Survey of Family Growth. , Chandra A, Copen CE, Stephen EH, Natl Health Stat Report. 2013 August 14; (67):1-18, 1 p following 19.

4. Future prospects. 2018 Male Contraceptive Initiative (MCI) March
www.malecontraceptive。。 ｏｒｇ/male-contraception-research/prospective-male-contraceptive-options/